Vincristine February 4, 2020 by veccmo Dogs: Immune-mediated thrombocytopenia: 0.02 mg/kg IV once MOA: disrupts microtubules in megakaryocytes; impairs phagocytosis by macrophages Pred + vinc (5 days) vs. pred alone (7 days) to reach >40K plts (ref) Caution: extravasation