1-4 mU/kg/min Can give test-dose of 4 mU/kg IV before starting CRI

Dogs: Immune-mediated thrombocytopenia: 0.02 mg/kg IV once MOA: disrupts microtubules in megakaryocytes; impairs phagocytosis by macrophages Pred + vinc (5 days) vs. pred alone (7 days) to reach >40K plts (ref) Caution: extravasation