Immunomodulator (ITP, IMHA): <20kg: 3 mg, >20 kg 6 mg PO q12h

Indications & Dose: Ventricular arrhythmias: Dog: 3-5 mg/kg PO q12h in combo with sotalol or atenolol Cat: 5 mg/kg PO q8h Mechanism of Action: Class IB: sodium channel blocker Adverse Effects:  GI effects at higher doses Hypotension Proarrhythmic Seizures (dogs)

Indications & Dose: Hypotension refractory to fluids: 0.1 – 1 mcg/kg/min CRI Typically start at 0.1-0.2 mcg/kg/min, titrate by 0.05-0.1 mcg/kg/min q5-10min until MAP is 65 mmHg or another pressor is added Preparation: Typically comes as 1 mg/ml. 4 ml added to 250 ml of D5W creates a 16 mcg/ml solution Ideally, should be given […]

Physiologic 0.05-0.2 mg/kg/day Supraphysiologic 0.2-0.45 mg/kg/day Anti-inflammatory 0.5-1.0 mg/kg/day Immunosuppressive 2mg/kg/day (dog) , 4mg/kg/day (cat)?

Indications & Dose: Dogs: Ventricular arrhythmias: 2-4 mg/kg IV slow; 20-50 mcg/kg/min CRI Chronic: 20-40 mg/kg PO q6-8h; 20-30 mg/kg PO q8h for sustained release Mechanism of Action: Class IA: sodium channel blocker Adverse Effects:  Hypotension Proarrhythmic Hypersensitivity reactions Brown hair reported in Doberman Pinschers after long-term use