Indications & Dose: Hypotension / vasopressor: 5-20 mcg/kg/min Titrate up q5-20 min ~5-10 mcg/kg/min ~ contractility ~10-20 mcg/kg/min ~ vasopressor Preparation: 12.5 mg/mL: add 10 mL to 250 mL saline/D5W/LRS = 0.5 mg/mL Adverse Effects: Arrhythmias Extravasation: local peripheral ischemia and necrosis/sloughing Seizures in cats? Mechanism of action: Alpha and beta-adrenergic agonist Catecholamine (precursor to […]

Indications &Dose: Anaphylaxis: CRI: 0.05 mcg/kg/min; titrate 0.01 – 0.025 mg/kg IM/IV; can repeat as needed CRI more effective than IV in dog anaphylaxis model (ref) CPR: Start with “low dose”  0.01 mg/kg  IV/IO q4min TIP: 0.1 mL per 10 kg After ~10 min, consider “high dose” 0.1 mg/kg IV/IO q4min TIP: 1.0 mL per […]

Indications & Dose: Tachyarrhythmias: 25-100 mcg/kg IV slow Max 500 mcg/kg 25-200 mcg/kg/min IV CRI Emergency Hypertension: 50-75 mcg/kg/min IV CRI Mechanism of Action: Beta1 blocker Adverse Effects:  Hypotension Extravasation & thrombophlebitis

Indications & Dose: Ethylene glycol toxicosis Dogs: CRI 7%: 8.6 mL/kg as bolus over 30 min then 1.43 mL/kg/h for 36-48h Cats Intermittent 20%: 5 mlLkg IV q6h x 5 doses, then q8h x 4 doses Adverse effects: CNS deprression metabolic acidosis osmotic diuresis Ethanol math: Get the highest proof possible C1 x V1 = […]

DOSES: Bolus: 2-6 mcg/kg CRI: 2-6 mcg/kg/h Reversal: Naloxone IV