Indications & Dose: Type I von Willebrand disease 1-3 μg/kg SC (can use the injectable solution or the nasal spray) for clinical bleeding – peak effect in 10 minutes, lasts around 2 hours, repeated doses less effective for 48 hours or so Central diabetes insipidus 1-4 drops of the intranasal spray into the nostril, conjunctival sac, vulva […]

Indications and Doses:  Sedation and analgesic (dogs/cats): best if used in conjunction with other agents 2-5 mcg/kg IV lasting approximately 20-30 minutes 5-15 mcg/kg IM 30-45 minutes, but may take up to 15 minutes to take full effect Constant rate infusion for anxious/fractious patients: 0.5-2 mcg/kg bolus, then 0.5-3 mcg/kg/hr Oromucosal gel can be used […]

Indications & Doses: Cluster seizures or status epilepticus: 0.5-1 mg/kg IV, intranasally, rectally Constant rate infusion: 0.1-2 mg/kg/hr (may crystallize in tubing; light sensitive) Skeletal muscle relaxant or anxiolytic: 0.5-2 mg/kg IV or PO q8-12h Adjunctive sedative: 0.2-0.5 mg/kg IV Reversal: Flumazenil IV Mechanism of Action: Benzodiazepine Precautions: Not recommended in cats due to idiosyncratic hepatic […]

Indications & Doses: Acute SVT: Dogs: 0.1 mg/kg IV over 1-2 minutes; can be repeated twice with at least 5 minutes between doses Cats: 0.2 mg/kg IV over 1-2 minutes; wait at least 15 minutes before dosing again Constant rate infusion: 0.15-0.25 mg/kg IV bolus slowly, then 5-20 mcg/kg/min Chronic SVT: Dogs: initially 1 mg/kg […]

Indications & Dose: Increase cardiac contractility: 1-20 mcg/kg/min Typically start at 5 mcg/kg/min Preparation: 12.5 mg/mL: add 10 mL to 250 mL saline = 0.5 mg/mL Max concentration: Add 20 mL to 50 mL saline = 5 mg/mL Adverse Effects: Arrhythmias Extravasation: inflammation, pain, necrosis (uncommon) Seizures in cats? Mechanism of action: Sympathomimetic: mostly beta1 […]